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The physical and emotional toll of TTR-FAP

The persistent decline in neurologic function associated with TTR-FAP is accompanied by significant decline in quality of life.18

The physical toll

The typical ongoing loss of ambulation associated with TTR-FAP has a significant impact on independence.11,18 Ultimately, patients may become bedridden and unable to care for themselves.17,18

Autonomic symptoms such as alternating bouts of constipation and diarrhea, erectile dysfunction, and weakness due to malabsorption and malnutrition may take a physical toll as well.5,10

In the end stage of TTR-FAP, patients require ongoing assistance and may
require hospitalization.17,18

The emotional toll

Along with its negative impact on their self-esteem, TTR-FAP patients may feel hopeless as well as fearful, bitter, and insecure.18

Today, support is available for your patients with TTR-FAP.

Connect your patients with TTR-FAP support resources

The toll on family

While the toll TTR-FAP takes on patients may be obvious, the toll on family members can also be considerable.18 Families often need advice, support, and information to deal with the impact of the disease on their lives.18

Genetic considerations

And because TTR-FAP is genetic, it can raise additional concerns for biological relatives worried about their own health. Genetic testing itself may trigger anxiety and depression, so adequate support is essential.19